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Estroven for Menopause Relief Sleep Cool & Calm Dietary Supplement Caplets. Naturally sourced black cohosh root extract, plus clinically proven soy isoflavones to help reduce the frequency and severity of hot flashes and night sweats. Melatonin, which is clinically proven to help you fall asleep easier and stay asleep, so you can wake up refreshed. Estroven Sleep Cool & Calm does not contain preservatives, yeast, wheat, gluten or lactose. Drug free & estrogen free. Gender: female.